Company Profile

Vertex Pharmaceuticals

Company Overview

At Vertex, we bring together the brightest minds in the relentless pursuit of creating transformative medicines for people with serious and life-threatening diseases. Founded in 1989 in Cambridge, Massachusetts, we are one of only a handful of biotechnology companies founded since 1976 that has discovered and developed four or more approved medicines in our own labs. In addition to the four medicines we’ve developed to treat the underlying cause of cystic fibrosis, we have ongoing research programs focused on the underlying mechanisms of other serious diseases.

Our U.S. headquarters are in Boston’s Innovation District, our International headquarters are located in London, UK, and we have research and development (R&D) sites and commercial offices in the U.S., Europe, Canada, Australia and Latin America. With more than two-thirds of our employees dedicated to research and development (R&D), we are consistently recognized as one of the industry’s top places to work, including nine consecutive years on Science magazine’s Top Employers list. For company updates and to learn more about us visit www.vrtx.com. You can also get to know us on Facebook, Twitter and YouTube.

Positions Available
  • 3 days ago

    Clinical Development Medical Director- Neurology

    Vertex Pharmaceuticals - Boston, Massachusetts, United States

    Job DescriptionGeneral Summary:The Clinical Development Medical Director will serve as the Medical Lead for Vertex clinical trials, working with cross-functional multidisciplinary study teams on clinical trial strategy, design and execution and serving as the Medical Monitor responsible for monitoring the safety of enrolled subjects on assigned trials. The incumbent will work on multiple trials in all Phases of clinical development, and may also participate in other selected projects in clinical ...

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  • 11 days ago

    Vertex Summer 2026 Intern, Clinical Science

    Vertex Pharmaceuticals - Boston, Massachusetts, United States

    Job DescriptionKickstart Your Career at Vertex!Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you'll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We're passionate about innovation, ...

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  • 16 days ago

    Senior Principal Research Scientist, Biomarkers Lead (Immunology)

    Vertex Pharmaceuticals - Boston, Massachusetts, United States

    Job DescriptionGeneral Summary:The Biomarkers Senior Principal Research Scientist (Associate Director) is an independent leader with advanced scientific knowledge and expertise in biomarker development who develops and implements the clinical biomarker strategy for one or more programs and implements the biomarker plan during clinical development with no/minimal guidance. Experience in authoring and supporting regulatory filings and applicable areas of these filings is required. The incumbent ...

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  • 19 days ago

    Associate Director, End User Compute

    Vertex Pharmaceuticals - Boston, Massachusetts, United States

    Job DescriptionVertex is seeking an experienced Associate Director to lead the day-to-day operations of our global End User Compute (EUC) platforms with a focus on end user experience of the highest quality. This role will focus on Modern Workstation Engineering & Architecture to deliver secure, compliant, and seamless Windows and Mac workstation and mobile experiences across Vertex's regulated life sciences environment. The successful candidate will drive operational excellence, governance, ...

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  • 25 days ago

    Clinical Development Medical Director (Heme)

    Vertex Pharmaceuticals - Boston, Massachusetts, United States

    Job DescriptionGeneral Summary:Vertex Pharmaceuticals is searching for an experienced Medical Director to lead strategic and tactical activities for a broad range of ongoing clinical development activities within the Hematology clinical development team. You will work as part of multidisciplinary cross-functional teams on clinical development strategy, clinical trial data analysis and publications, clinical development related data generation activities, ongoing clinical trial execution, and ...

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  • 25 days ago

    Global Medical Director, Povetacicept

    Vertex Pharmaceuticals - Boston, Massachusetts, United States

    Job DescriptionGeneral Summary:The Global Medical Affairs Strategy Medical Director will provide medical leadership for the Povetacicept programs. Povetacicept (pove) is an enhanced, dual BAFF/APRIL inhibitor in pivotal development for the treatment of IgA Nephropathy (IgAN), primary Membranous Nephropathy (pMN), and generalized Myasthenia Gravis (gMG) that has best-in-class and pipeline-in-a-product potential across a variety of autoimmune diseases. This role will be responsible for developing ...

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  • 25 days ago

    Director, Health Economics & Outcomes Research

    Vertex Pharmaceuticals - Boston, Massachusetts, United States

    Job DescriptionVertex is a global biotechnology company that operates at the forefront of scientific innovation. We have brought multiple breakthrough therapies to patients with Cystic Fibrosis (CF) and advanced novel treatments such as CASGEVY, a gene therapy for sickle cell disease and beta-thalassemia, and JOURNAVX, the first new class of medicine for moderate-to-severe acute pain in more than two decades. Our research pipeline spans more than a dozen programs targeting the underlying mechanisms ...

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  • 25 days ago

    Medical Writing Manager (Hybrid)

    Vertex Pharmaceuticals - VERTEX ONE, United States

    Job DescriptionGeneral Summary:The Medical Writing Science Manager is responsible for preparing moderately complex clinical and regulatory documents and represents Medical Writing Science as a cross-functional team member at clinical study level activities. This role contributes scientific knowledge and analytical skills to the development of clinical regulatory documentation, under minimal supervision. Key Duties and Responsibilities:Authors moderately complex clinical regulatory documents ...

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  • 25 days ago

    Medical Affairs Director - CF (Hybrid)

    Vertex Pharmaceuticals - Boston, Massachusetts, United States

    Job DescriptionGeneral Summary:The Medical Affairs Director, Cystic Fibrosis (CF) will provide medical leadership for the Medical Affairs Department in our CF therapeutic area. This role will be accountable for working with the medical team for the development and implementation of the US Medical strategy and plans. This role will work in partnership with other cross-functional team colleagues to ensure access to the company's products, and to develop and implement cross functional plans aligned ...

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  • 25 days ago

    Medical Affairs Medical Director- Pain

    Vertex Pharmaceuticals - Boston, Massachusetts, United States

    Job DescriptionGeneral Summary:The Medical Director, Medical Affairs Strategy will provide medical leadership for the US Pain team and will be responsible for developing the medical strategy and medical plan as well as executing against the medical plan for US Pain. This role will lead a team that will collaborate closely with cross-functional groups to ensure that scientific and medical strategies are aligned with broader corporate and key stakeholder needs as well as ensuring the voice of ...

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